Simple Derivation of Spinal Motor Neurons from ESCs/iPSCs Using Sendai Virus Vectors

Amyotrophic lateral sclerosis (ALS) is a progressive and fatal degenerative disorder of motor neurons (MNs). Embryonic stem cells (ESCs)/induced pluripotent stem cells (iPSCs) now help us to understand the pathomechanisms of ALS via disease modeling. Various methods to differentiate ESCs/iPSCs into...

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Detalhes bibliográficos
Publicado no:Mol Ther Methods Clin Dev
Main Authors: Goto, Kazuya, Imamura, Keiko, Komatsu, Kenichi, Mitani, Kohnosuke, Aiba, Kazuhiro, Nakatsuji, Norio, Inoue, Makoto, Kawata, Akihiro, Yamashita, Hirofumi, Takahashi, Ryosuke, Inoue, Haruhisa
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363292/
https://ncbi.nlm.nih.gov/pubmed/28344997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2016.12.007
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