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Masked Chimeric Antigen Receptor for Tumor-Specific Activation
Adoptive cellular therapy based on chimeric antigen receptor (CAR)-engineered T (CAR-T) cells is a powerful form of cancer immunotherapy. CAR-T cells can be redirected to specifically recognize tumor-associated antigens (TAAs) and induce high levels of antitumor activity. However, they may also disp...
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Publicado no: | Mol Ther |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society of Gene & Cell Therapy
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5363190/ https://ncbi.nlm.nih.gov/pubmed/28129121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2016.10.011 |
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