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Masked Chimeric Antigen Receptor for Tumor-Specific Activation

Adoptive cellular therapy based on chimeric antigen receptor (CAR)-engineered T (CAR-T) cells is a powerful form of cancer immunotherapy. CAR-T cells can be redirected to specifically recognize tumor-associated antigens (TAAs) and induce high levels of antitumor activity. However, they may also disp...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Han, Xiaolu, Bryson, Paul D., Zhao, Yifan, Cinay, Gunce E., Li, Si, Guo, Yunfei, Siriwon, Natnaree, Wang, Pin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363190/
https://ncbi.nlm.nih.gov/pubmed/28129121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2016.10.011
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