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Gd-TEMDO: Design, synthesis and MRI application

A simple Ugi tetrazole multicomponent reaction allows the synthesis of a novel macrocyclic cyclen derivative with four appendant tetrazole arms in just two steps in excellent yields. This ligand, called TEMDO, turns out to be a very good complexator of lanthanoid metals. Here we describe the design,...

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Detalhes bibliográficos
Publicado no:Chemistry
Main Authors: Boltjes, André, Shrinidhi, Annadka, van de Kolk, C.W.A. Kees, Herdtweck, Eberhardt, Dömling, Alexander S.S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363076/
https://ncbi.nlm.nih.gov/pubmed/26991633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201600720
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