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MCR synthesis of a tetracyclic tetrazole scaffold
Scaffold diversity is key in the ongoing exercise of discovery of novel bioactive compounds using high throughput screening (HTS). Based on the Ugi tetrazole synthesis we have designed novel bi- and tri-cyclic scaffolds featuring interesting pharmacophore properties. The compounds of the scaffold (B...
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| Опубликовано в: : | Bioorg Med Chem |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4733496/ https://ncbi.nlm.nih.gov/pubmed/25630499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2014.12.021 |
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