Hypercholesterolemia downregulates autophagy in the rat heart

BACKGROUND: We have previously shown that efficiency of ischemic conditioning is diminished in hypercholesterolemia and that autophagy is necessary for cardioprotection. However, it is unknown whether isolated hypercholesterolemia disturbs autophagy or the mammalian target of rapamycin (mTOR) pathwa...

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Dades bibliogràfiques
Publicat a:Lipids Health Dis
Autors principals: Giricz, Zoltán, Koncsos, Gábor, Rajtík, Tomáš, Varga, Zoltán V., Baranyai, Tamás, Csonka, Csaba, Szobi, Adrián, Adameová, Adriana, Gottlieb, Roberta A., Ferdinandy, Péter
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363032/
https://ncbi.nlm.nih.gov/pubmed/28330474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12944-017-0455-0
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