Isolated hypercholesterolemia leads to steatosis in the liver without affecting the pancreas

Abstract Background Lipid accumulation in the liver and pancreas is primarily caused by combined hyperlipidemia. However, the effect of isolated hypercholesterolemia without hypertriglyceridemia is not fully described. Therefore, our aim was to investigate whether hypercholesterolemia alone leads to...

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Detalhes bibliográficos
Main Authors: Csaba Csonka, Tamás Baranyai, László Tiszlavicz, Hedvig Fébel, Gergő Szűcs, Zoltán V. Varga, Márta Sárközy, László G. Puskás, Otilia Antal, Andrea Siska, Imre Földesi, Péter Ferdinandy, László Czakó, Tamás Csont
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2017-07-01
Colecção:Lipids in Health and Disease
Assuntos:
Fatty acid desaturase (FADS)
Isolated hypercholesterolemia
Lipidomics
Non-alcoholic fatty liver disease
Stearoyl-coenzyme a desaturase (SCD)
Lipotoxicity
Acesso em linha:http://link.springer.com/article/10.1186/s12944-017-0537-z
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