Hypercholesterolemia downregulates autophagy in the rat heart

BACKGROUND: We have previously shown that efficiency of ischemic conditioning is diminished in hypercholesterolemia and that autophagy is necessary for cardioprotection. However, it is unknown whether isolated hypercholesterolemia disturbs autophagy or the mammalian target of rapamycin (mTOR) pathwa...

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Detalles Bibliográficos
Publicado en:Lipids Health Dis
Main Authors: Giricz, Zoltán, Koncsos, Gábor, Rajtík, Tomáš, Varga, Zoltán V., Baranyai, Tamás, Csonka, Csaba, Szobi, Adrián, Adameová, Adriana, Gottlieb, Roberta A., Ferdinandy, Péter
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2017
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363032/
https://ncbi.nlm.nih.gov/pubmed/28330474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12944-017-0455-0
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