Cross-neutralizing anti-HIV-1 human single chain variable fragments(scFvs) against CD4 binding site and N332 glycan identified from a recombinant phage library

More than 50% of HIV-1 infection globally is caused by subtype_C viruses. Majority of the broadly neutralizing antibodies (bnAbs) targeting HIV-1 have been isolated from non-subtype_C infected donors. Mapping the epitope specificities of bnAbs provides useful information for vaccine design. Recombin...

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Vydáno v:Sci Rep
Hlavní autoři: Khan, Lubina, Kumar, Rajesh, Thiruvengadam, Ramachandran, Parray, Hilal Ahmad, Makhdoomi, Muzamil Ashraf, Kumar, Sanjeev, Aggarwal, Heena, Mohata, Madhav, Hussain, Abdul Wahid, Das, Raksha, Varadarajan, Raghavan, Bhattacharya, Jayanta, Vajpayee, Madhu, Murugavel, K. G., Solomon, Suniti, Sinha, Subrata, Luthra, Kalpana
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362912/
https://ncbi.nlm.nih.gov/pubmed/28332627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45163
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