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A novel strategy for efficient production of anti-V3 human scFvs against HIV-1 clade C

BACKGROUND: Production of human monoclonal antibodies that exhibit broadly neutralizing activity is needed for preventing HIV-1 infection, however only a few such antibodies have been generated till date. Isolation of antibodies by the hybridoma technology is a cumbersome process with fewer yields....

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Détails bibliographiques
Auteurs principaux: Kumar, Rajesh, Andrabi, Raiees, Tiwari, Ashutosh, Prakash, Somi Sankaran, Wig, Naveet, Dutta, Durgashree, Sankhyan, Anurag, Khan, Lubina, Sinha, Subrata, Luthra, Kalpana
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536577/
https://ncbi.nlm.nih.gov/pubmed/23153214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-12-87
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