Janus-faced Acrolein prevents allergy but accelerates tumor growth by promoting immunoregulatory Foxp3+ cells: Mouse model for passive respiratory exposure

Acrolein, a highly reactive unsaturated aldehyde, is generated in large amounts during smoking and is best known for its genotoxic capacity. Here, we aimed to assess whether acrolein at concentrations relevant for smokers may also exert immunomodulatory effects that could be relevant in allergy or c...

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Publicat a:Sci Rep
Autors principals: Roth-Walter, Franziska, Bergmayr, Cornelia, Meitz, Sarah, Buchleitner, Stefan, Stremnitzer, Caroline, Fazekas, Judit, Moskovskich, Anna, Müller, Mario A., Roth, Georg A., Manzano-Szalai, Krisztina, Dvorak, Zdenek, Neunkirchner, Alina, Jensen-Jarolim, Erika
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362909/
https://ncbi.nlm.nih.gov/pubmed/28332605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45067
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