Janus-faced Acrolein prevents allergy but accelerates tumor growth by promoting immunoregulatory Foxp3+ cells: Mouse model for passive respiratory exposure

Acrolein, a highly reactive unsaturated aldehyde, is generated in large amounts during smoking and is best known for its genotoxic capacity. Here, we aimed to assess whether acrolein at concentrations relevant for smokers may also exert immunomodulatory effects that could be relevant in allergy or c...

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Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Roth-Walter, Franziska, Bergmayr, Cornelia, Meitz, Sarah, Buchleitner, Stefan, Stremnitzer, Caroline, Fazekas, Judit, Moskovskich, Anna, Müller, Mario A., Roth, Georg A., Manzano-Szalai, Krisztina, Dvorak, Zdenek, Neunkirchner, Alina, Jensen-Jarolim, Erika
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362909/
https://ncbi.nlm.nih.gov/pubmed/28332605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45067
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