CHL1 hypermethylation as a potential biomarker of poor prognosis in breast cancer

The CHL1 gene encodes a cell-adhesion molecule proposed as being a putative tumour-suppressor gene in breast cancer (BC). However, neither the underlying molecular mechanisms nor the clinical value of CHL1 downregulation in BC has been explored. The methylation status of three CpG sites in the CHL1...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Martín-Sánchez, Esperanza, Mendaza, Saioa, Ulazia-Garmendia, Ane, Monreal-Santesteban, Iñaki, Blanco-Luquin, Idoia, Córdoba, Alicia, Vicente-García, Francisco, Pérez-Janices, Noemí, Escors, David, Megías, Diego, López-Serra, Paula, Esteller, Manel, Illarramendi, José Juan, Guerrero-Setas, David
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362523/
https://ncbi.nlm.nih.gov/pubmed/28178655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15004
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