CHL1 hypermethylation as a potential biomarker of poor prognosis in breast cancer

The CHL1 gene encodes a cell-adhesion molecule proposed as being a putative tumour-suppressor gene in breast cancer (BC). However, neither the underlying molecular mechanisms nor the clinical value of CHL1 downregulation in BC has been explored. The methylation status of three CpG sites in the CHL1...

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發表在:Oncotarget
Main Authors: Martín-Sánchez, Esperanza, Mendaza, Saioa, Ulazia-Garmendia, Ane, Monreal-Santesteban, Iñaki, Blanco-Luquin, Idoia, Córdoba, Alicia, Vicente-García, Francisco, Pérez-Janices, Noemí, Escors, David, Megías, Diego, López-Serra, Paula, Esteller, Manel, Illarramendi, José Juan, Guerrero-Setas, David
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2017
主題:
Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362523/
https://ncbi.nlm.nih.gov/pubmed/28178655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15004
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