CHL1 hypermethylation as a potential biomarker of poor prognosis in breast cancer

The CHL1 gene encodes a cell-adhesion molecule proposed as being a putative tumour-suppressor gene in breast cancer (BC). However, neither the underlying molecular mechanisms nor the clinical value of CHL1 downregulation in BC has been explored. The methylation status of three CpG sites in the CHL1...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Martín-Sánchez, Esperanza, Mendaza, Saioa, Ulazia-Garmendia, Ane, Monreal-Santesteban, Iñaki, Blanco-Luquin, Idoia, Córdoba, Alicia, Vicente-García, Francisco, Pérez-Janices, Noemí, Escors, David, Megías, Diego, López-Serra, Paula, Esteller, Manel, Illarramendi, José Juan, Guerrero-Setas, David
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2017
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362523/
https://ncbi.nlm.nih.gov/pubmed/28178655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15004
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