טוען...
Anti-melanoma vaccines engineered to simultaneously modulate cytokine priming and silence PD-L1 characterized using ex vivo myeloid-derived suppressor cells as a readout of therapeutic efficacy
Efficacious antitumor vaccines strongly stimulate cancer-specific effector T cells and counteract the activity of tumor-infiltrating immunosuppressive cells. We hypothesised that combining cytokine expression with silencing programmed cell death ligand 1 (PD-L1) could potentiate anticancer immune re...
שמור ב:
הוצא לאור ב: | Oncoimmunology |
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Main Authors: | , , , , , , , , , , |
פורמט: | Artigo |
שפה: | Inglês |
יצא לאור: |
Taylor & Francis
2014
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נושאים: | |
גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4355828/ https://ncbi.nlm.nih.gov/pubmed/25954597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.945378 |
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