Ex vivo generation of myeloid-derived suppressor cells that model the tumor immunosuppressive environment in colorectal cancer

Myeloid-derived suppressor cells (MDSC) are a heterogeneous population of cells that accumulate in tumor-bearing subjects and which strongly inhibit anti-cancer immune responses. To study the biology of MDSC in colorectal cancer (CRC), we cultured bone marrow cells in conditioned medium from CT26 ce...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Dufait, Inès, Schwarze, Julia Katharina, Liechtenstein, Therese, Leonard, Wim, Jiang, Heng, Escors, David, De Ridder, Mark, Breckpot, Karine
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4494944/
https://ncbi.nlm.nih.gov/pubmed/25869209
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