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The GlcN6P cofactor serves multiple catalytic roles in the glmS ribozyme
RNA enzymes have remarkably diverse biological roles despite having limited chemical diversity. Protein enzymes enhance their reactivity through recruitment of cofactors. The naturally occurring glmS ribozyme uses the glucosamine-6-phosphate (GlcN6P) organic cofactor for phosphodiester bond cleavage...
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| Pubblicato in: | Nat Chem Biol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5362308/ https://ncbi.nlm.nih.gov/pubmed/28192411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2300 |
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