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The GlcN6P cofactor serves multiple catalytic roles in the glmS ribozyme
RNA enzymes have remarkably diverse biological roles despite having limited chemical diversity. Protein enzymes enhance their reactivity through recruitment of cofactors. The naturally occurring glmS ribozyme uses the glucosamine-6-phosphate (GlcN6P) organic cofactor for phosphodiester bond cleavage...
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| Publicado en: | Nat Chem Biol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5362308/ https://ncbi.nlm.nih.gov/pubmed/28192411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2300 |
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