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The GlcN6P cofactor serves multiple catalytic roles in the glmS ribozyme

RNA enzymes have remarkably diverse biological roles despite having limited chemical diversity. Protein enzymes enhance their reactivity through recruitment of cofactors. The naturally occurring glmS ribozyme uses the glucosamine-6-phosphate (GlcN6P) organic cofactor for phosphodiester bond cleavage...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nat Chem Biol
Päätekijät: Bingaman, Jamie L., Zhang, Sixue, Stevens, David R., Yennawar, Neela H., Hammes-Schiffer, Sharon, Bevilacqua, Philip C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362308/
https://ncbi.nlm.nih.gov/pubmed/28192411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2300
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