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Assessing the Potential Effects of Active Site Mg(2+) Ions in the glmS Ribozyme–Cofactor Complex

[Image: see text] Ribozymes employ diverse catalytic strategies in their self-cleavage mechanisms, including the use of divalent metal ions. This work explores the effects of Mg(2+) ions in the active site of the glmS ribozyme–GlcN6P cofactor complex using computational methods. Deleterious and pote...

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Detalhes bibliográficos
Publicado no:J Phys Chem Lett
Main Authors: Zhang, Sixue, Stevens, David R., Goyal, Puja, Bingaman, Jamie L., Bevilacqua, Philip C., Hammes-Schiffer, Sharon
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2016
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5117136/
https://ncbi.nlm.nih.gov/pubmed/27677922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpclett.6b01854
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