Olfactory receptor accessory proteins play crucial roles in receptor function and gene choice

Each of the olfactory sensory neurons (OSNs) chooses to express a single G protein-coupled olfactory receptor (OR) from a pool of hundreds. Here, we show the receptor transporting protein (RTP) family members play a dual role in both normal OR trafficking and determining OR gene choice probabilities...

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Vydáno v:eLife
Hlavní autoři: Sharma, Ruchira, Ishimaru, Yoshiro, Davison, Ian, Ikegami, Kentaro, Chien, Ming-Shan, You, Helena, Chi, Quiyi, Kubota, Momoka, Yohda, Masafumi, Ehlers, Michael, Matsunami, Hiroaki
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2017
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362263/
https://ncbi.nlm.nih.gov/pubmed/28262096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.21895
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