Improved health-span and lifespan in mtDNA mutator mice treated with the mitochondrially targeted antioxidant SkQ1

MtDNA mutator mice exhibit marked features of premature aging. We find that these mice treated from age of ≈100 days with the mitochondria-targeted antioxidant SkQ1 showed a delayed appearance of traits of aging such as kyphosis, alopecia, lowering of body temperature, body weight loss, as well as a...

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Publicado en:Aging (Albany NY)
Autores principales: Shabalina, Irina G., Vyssokikh, Mikhail Yu., Gibanova, Natalia, Csikasz, Robert I., Edgar, Daniel, Hallden-Waldemarson, Anne, Rozhdestvenskaya, Zinaida, Bakeeva, Lora E., Vays, Valeria B., Pustovidko, Antonina V., Skulachev, Maxim V., Cannon, Barbara, Skulachev, Vladimir P., Nedergaard, Jan
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5361666/
https://ncbi.nlm.nih.gov/pubmed/28209927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101174
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