Improved health-span and lifespan in mtDNA mutator mice treated with the mitochondrially targeted antioxidant SkQ1

MtDNA mutator mice exhibit marked features of premature aging. We find that these mice treated from age of ≈100 days with the mitochondria-targeted antioxidant SkQ1 showed a delayed appearance of traits of aging such as kyphosis, alopecia, lowering of body temperature, body weight loss, as well as a...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Aging (Albany NY)
Κύριοι συγγραφείς: Shabalina, Irina G., Vyssokikh, Mikhail Yu., Gibanova, Natalia, Csikasz, Robert I., Edgar, Daniel, Hallden-Waldemarson, Anne, Rozhdestvenskaya, Zinaida, Bakeeva, Lora E., Vays, Valeria B., Pustovidko, Antonina V., Skulachev, Maxim V., Cannon, Barbara, Skulachev, Vladimir P., Nedergaard, Jan
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Impact Journals LLC 2017
Θέματα:
Research Paper
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5361666/
https://ncbi.nlm.nih.gov/pubmed/28209927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101174
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