Improved health-span and lifespan in mtDNA mutator mice treated with the mitochondrially targeted antioxidant SkQ1

MtDNA mutator mice exhibit marked features of premature aging. We find that these mice treated from age of ≈100 days with the mitochondria-targeted antioxidant SkQ1 showed a delayed appearance of traits of aging such as kyphosis, alopecia, lowering of body temperature, body weight loss, as well as a...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Shabalina, Irina G., Vyssokikh, Mikhail Yu., Gibanova, Natalia, Csikasz, Robert I., Edgar, Daniel, Hallden-Waldemarson, Anne, Rozhdestvenskaya, Zinaida, Bakeeva, Lora E., Vays, Valeria B., Pustovidko, Antonina V., Skulachev, Maxim V., Cannon, Barbara, Skulachev, Vladimir P., Nedergaard, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5361666/
https://ncbi.nlm.nih.gov/pubmed/28209927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101174
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