Improved health-span and lifespan in mtDNA mutator mice treated with the mitochondrially targeted antioxidant SkQ1

MtDNA mutator mice exhibit marked features of premature aging. We find that these mice treated from age of ≈100 days with the mitochondria-targeted antioxidant SkQ1 showed a delayed appearance of traits of aging such as kyphosis, alopecia, lowering of body temperature, body weight loss, as well as a...

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Bibliografski detalji
Izdano u:Aging (Albany NY)
Glavni autori: Shabalina, Irina G., Vyssokikh, Mikhail Yu., Gibanova, Natalia, Csikasz, Robert I., Edgar, Daniel, Hallden-Waldemarson, Anne, Rozhdestvenskaya, Zinaida, Bakeeva, Lora E., Vays, Valeria B., Pustovidko, Antonina V., Skulachev, Maxim V., Cannon, Barbara, Skulachev, Vladimir P., Nedergaard, Jan
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2017
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5361666/
https://ncbi.nlm.nih.gov/pubmed/28209927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101174
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