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Effects of Covalent Modification by 4-hydroxy-2-nonenal on the Noncovalent Oligomerization of Ubiquitin

When lipid membranes containing ω-6 polyunsaturated fatty acyl chains are subjected to oxidative stress, one of the reaction products is 4-hydroxy-2-nonenal (HNE) – a chemically reactive short chain alkenal that can covalently modify proteins. The ubiquitin proteasome system is involved in the clear...

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Detalhes bibliográficos
Publicado no:J Mass Spectrom
Main Authors: Grasso, Giuseppe, Axelsen, Paul H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360464/
https://ncbi.nlm.nih.gov/pubmed/27862610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jms.3897
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