Association between fatty acid metabolism in the brain and Alzheimer disease neuropathology and cognitive performance: A nontargeted metabolomic study

BACKGROUND: The metabolic basis of Alzheimer disease (AD) pathology and expression of AD symptoms is poorly understood. Omega-3 and -6 fatty acids have previously been linked to both protective and pathogenic effects in AD. However, to date little is known about how the abundance of these species is...

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Udgivet i:PLoS Med
Main Authors: Snowden, Stuart G., Ebshiana, Amera A., Hye, Abdul, An, Yang, Pletnikova, Olga, O’Brien, Richard, Troncoso, John, Legido-Quigley, Cristina, Thambisetty, Madhav
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360226/
https://ncbi.nlm.nih.gov/pubmed/28323825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1002266
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