Cysteine mutagenesis improves the production without abrogating antigenicity of a recombinant protein vaccine candidate for human chagas disease

A therapeutic vaccine for human Chagas disease is under development by the Sabin Vaccine Institute Product Development Partnership. The aim of the vaccine is to significantly reduce the parasite burden of Trypanosoma cruzi in humans, either as a standalone product or in combination with conventional...

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Bibliografische gegevens
Gepubliceerd in:Hum Vaccin Immunother
Hoofdauteurs: Seid, Christopher A., Jones, Kathryn M., Pollet, Jeroen, Keegan, Brian, Hudspeth, Elissa, Hammond, Molly, Wei, Junfei, McAtee, C. Patrick, Versteeg, Leroy, Gutierrez, Amanda, Liu, Zhuyun, Zhan, Bin, Respress, Jonathan L., Strych, Ulrich, Bottazzi, Maria Elena, Hotez, Peter J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2016
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Research Papers
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360114/
https://ncbi.nlm.nih.gov/pubmed/27737611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2016.1242540
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