Expression and purification of an engineered, yeast-expressed Leishmania donovani nucleoside hydrolase with immunogenic properties

Leishmania donovani is the major cause of visceral leishmaniasis (kala-azar), now recognized as the parasitic disease with the highest level of mortality second only to malaria. No human vaccine is currently available. A 36 kDa L. donovani nucleoside hydrolase (LdNH36) surface protein has been previ...

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Detalhes bibliográficos
Publicado no:Hum Vaccin Immunother
Main Authors: Hudspeth, Elissa M., Wang, Qian, Seid, Christopher A., Hammond, Molly, Wei, Junfei, Liu, Zhuyun, Zhan, Bin, Pollet, Jeroen, Heffernan, Michael J., McAtee, C. Patrick, Engler, David A., Matsunami, Risë K., Strych, Ulrich, Asojo, Oluwatoyin A., Hotez, Peter J., Bottazzi, Maria Elena
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964838/
https://ncbi.nlm.nih.gov/pubmed/26839079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2016.1139254
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