Expression and purification of an engineered, yeast-expressed Leishmania donovani nucleoside hydrolase with immunogenic properties

Leishmania donovani is the major cause of visceral leishmaniasis (kala-azar), now recognized as the parasitic disease with the highest level of mortality second only to malaria. No human vaccine is currently available. A 36 kDa L. donovani nucleoside hydrolase (LdNH36) surface protein has been previ...

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Bibliografiske detaljer
Udgivet i:Hum Vaccin Immunother
Main Authors: Hudspeth, Elissa M., Wang, Qian, Seid, Christopher A., Hammond, Molly, Wei, Junfei, Liu, Zhuyun, Zhan, Bin, Pollet, Jeroen, Heffernan, Michael J., McAtee, C. Patrick, Engler, David A., Matsunami, Risë K., Strych, Ulrich, Asojo, Oluwatoyin A., Hotez, Peter J., Bottazzi, Maria Elena
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2016
Fag:
Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964838/
https://ncbi.nlm.nih.gov/pubmed/26839079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2016.1139254
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