Expression and purification of an engineered, yeast-expressed Leishmania donovani nucleoside hydrolase with immunogenic properties

Leishmania donovani is the major cause of visceral leishmaniasis (kala-azar), now recognized as the parasitic disease with the highest level of mortality second only to malaria. No human vaccine is currently available. A 36 kDa L. donovani nucleoside hydrolase (LdNH36) surface protein has been previ...

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Publicado en:Hum Vaccin Immunother
Autores principales: Hudspeth, Elissa M., Wang, Qian, Seid, Christopher A., Hammond, Molly, Wei, Junfei, Liu, Zhuyun, Zhan, Bin, Pollet, Jeroen, Heffernan, Michael J., McAtee, C. Patrick, Engler, David A., Matsunami, Risë K., Strych, Ulrich, Asojo, Oluwatoyin A., Hotez, Peter J., Bottazzi, Maria Elena
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2016
Materias:
Research Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964838/
https://ncbi.nlm.nih.gov/pubmed/26839079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2016.1139254
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