Vaccine-Linked Chemotherapy Improves Benznidazole Efficacy for Acute Chagas Disease

Chagas disease affects 6 to 7 million people worldwide, resulting in significant disease burdens and health care costs in countries of endemicity. Chemotherapeutic treatment is restricted to two parasiticidal drugs, benznidazole and nifurtimox. Both drugs are highly effective during acute disease bu...

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Dettagli Bibliografici
Pubblicato in:Infect Immun
Autori principali: Jones, Kathryn, Versteeg, Leroy, Damania, Ashish, Keegan, Brian, Kendricks, April, Pollet, Jeroen, Cruz-Chan, Julio Vladimir, Gusovsky, Fabian, Hotez, Peter J., Bottazzi, Maria Elena
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2018
Soggetti:
Microbial Immunity and Vaccines
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865041/
https://ncbi.nlm.nih.gov/pubmed/29311242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00876-17
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