Vaccine-Linked Chemotherapy Improves Benznidazole Efficacy for Acute Chagas Disease

Chagas disease affects 6 to 7 million people worldwide, resulting in significant disease burdens and health care costs in countries of endemicity. Chemotherapeutic treatment is restricted to two parasiticidal drugs, benznidazole and nifurtimox. Both drugs are highly effective during acute disease bu...

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Опубликовано в: :Infect Immun
Главные авторы: Jones, Kathryn, Versteeg, Leroy, Damania, Ashish, Keegan, Brian, Kendricks, April, Pollet, Jeroen, Cruz-Chan, Julio Vladimir, Gusovsky, Fabian, Hotez, Peter J., Bottazzi, Maria Elena
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2018
Предметы:
Microbial Immunity and Vaccines
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865041/
https://ncbi.nlm.nih.gov/pubmed/29311242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00876-17
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