Vasohibin 2 reduces chemosensitivity to gemcitabine in pancreatic cancer cells via Jun proto-oncogene dependent transactivation of ribonucleotide reductase regulatory subunit M2

BACKGROUND: Vasohibin 2 (VASH2) has previously been identified as an agiogenenic factor and a cancer related protein. Here we investigated the association of VASH2 expression and chemoresistance in pancreatic cancer. METHODS: Immunohistochemical staining for VASH2 was performed on 102 human pancreat...

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Bibliografiske detaljer
Udgivet i:Mol Cancer
Main Authors: Tu, Min, Li, Haifeng, Lv, Nan, Xi, Chunhua, Lu, Zipeng, Wei, Jishu, Chen, Jianmin, Guo, Feng, Jiang, Kuirong, Song, Guoxin, Gao, Wentao, Miao, Yi
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360034/
https://ncbi.nlm.nih.gov/pubmed/28327155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-017-0619-6
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