Identification of an enzyme in human kidney that correctly processes prorenin.

Using pure recombinant human prorenin as a substrate, we have identified an enzyme in human kidney that accurately processes prorenin to active renin (EC 3.4.23.15). In the crude homogenate, the predominant activity of this potential renin-processing enzyme (RPE) converted the Mr 47,000 inactive pro...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Shinagawa, T, Do, Y S, Baxter, J D, Carilli, C, Schilling, J, Hsueh, W A
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1990
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53597/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2408045/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.5.1927
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