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Identification of an enzyme in human kidney that correctly processes prorenin.

Using pure recombinant human prorenin as a substrate, we have identified an enzyme in human kidney that accurately processes prorenin to active renin (EC 3.4.23.15). In the crude homogenate, the predominant activity of this potential renin-processing enzyme (RPE) converted the Mr 47,000 inactive pro...

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Autors principals: Shinagawa, T, Do, Y S, Baxter, J D, Carilli, C, Schilling, J, Hsueh, W A
Format: Artigo
Idioma:Inglês
Publicat: 1990
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC53597/
https://ncbi.nlm.nih.gov/pubmed/2408045
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