Autoantibodies to calpastatin (an endogenous inhibitor for calcium-dependent neutral protease, calpain) in systemic rheumatic diseases.

We identified an autoantibody that reacts with calpastatin [an inhibitor protein of the calcium-dependent neutral protease calpain (EC 3.4.22.17)]. In early immunoblot studies, sera from patients with rheumatoid arthritis (RA) recognized unidentified 60-, 45-, and 75-kDa proteins in HeLa cell extrac...

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Detalhes bibliográficos
Main Authors: Mimori, T, Suganuma, K, Tanami, Y, Nojima, T, Matsumura, M, Fujii, T, Yoshizawa, T, Suzuki, K, Akizuki, M
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC41320/
https://ncbi.nlm.nih.gov/pubmed/7638179
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