Inhibition of Mammalian Target of Rapamycin (mTOR) Signaling in the Insular Cortex Alleviates Neuropathic Pain after Peripheral Nerve Injury

Injury of peripheral nerves can trigger neuropathic pain, producing allodynia and hyperalgesia via peripheral and central sensitization. Recent studies have focused on the role of the insular cortex (IC) in neuropathic pain. Because the IC is thought to store pain-related memories, translational reg...

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Bibliographische Detailangaben
Veröffentlicht in:Front Mol Neurosci
Hauptverfasser: Kwon, Minjee, Han, Jeongsoo, Kim, Un Jeng, Cha, Myeounghoon, Um, Sun Woo, Bai, Sun Joon, Hong, Seong-Karp, Lee, Bae Hwan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5359287/
https://ncbi.nlm.nih.gov/pubmed/28377693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00079
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