Inhibition of Mammalian Target of Rapamycin (mTOR) Signaling in the Insular Cortex Alleviates Neuropathic Pain after Peripheral Nerve Injury

Injury of peripheral nerves can trigger neuropathic pain, producing allodynia and hyperalgesia via peripheral and central sensitization. Recent studies have focused on the role of the insular cortex (IC) in neuropathic pain. Because the IC is thought to store pain-related memories, translational reg...

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Vydáno v:Front Mol Neurosci
Hlavní autoři: Kwon, Minjee, Han, Jeongsoo, Kim, Un Jeng, Cha, Myeounghoon, Um, Sun Woo, Bai, Sun Joon, Hong, Seong-Karp, Lee, Bae Hwan
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5359287/
https://ncbi.nlm.nih.gov/pubmed/28377693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00079
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