Inhibition of Mammalian Target of Rapamycin (mTOR) Signaling in the Insular Cortex Alleviates Neuropathic Pain after Peripheral Nerve Injury

Injury of peripheral nerves can trigger neuropathic pain, producing allodynia and hyperalgesia via peripheral and central sensitization. Recent studies have focused on the role of the insular cortex (IC) in neuropathic pain. Because the IC is thought to store pain-related memories, translational reg...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Kwon, Minjee, Han, Jeongsoo, Kim, Un Jeng, Cha, Myeounghoon, Um, Sun Woo, Bai, Sun Joon, Hong, Seong-Karp, Lee, Bae Hwan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5359287/
https://ncbi.nlm.nih.gov/pubmed/28377693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00079
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