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p73 induction after DNA damage is regulated by checkpoint kinases Chk1 and Chk2
The checkpoint kinases Chk1 and Chk2 are central to the induction of cell cycle arrest, DNA repair, and apoptosis as elements in the DNA-damage checkpoint. We report here that in several human tumor cell lines, Chk1 and Chk2 control the induction of the p53 related transcription factor p73 in respon...
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| Publié dans: | Genes Dev |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Cold Spring Harbor Laboratory Press
2004
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC535915/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15601819/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1221004 |
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