Applying antibody-sensitive hypervariable region 1-deleted hepatitis C virus to the study of escape pathways of neutralizing human monoclonal antibody AR5A

Hepatitis C virus (HCV) is a major cause of end-stage liver diseases. With 3–4 million new HCV infections yearly, a vaccine is urgently needed. A better understanding of virus escape from neutralizing antibodies and their corresponding epitopes are important for this effort. However, for viral isola...

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Bibliographic Details
Published in:PLoS Pathog
Main Authors: Velázquez-Moctezuma, Rodrigo, Law, Mansun, Bukh, Jens, Prentoe, Jannick
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358973/
https://ncbi.nlm.nih.gov/pubmed/28231271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006214
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