Chromosome conformation elucidates regulatory relationships in developing human brain

Three-dimensional physical interactions within chromosomes dynamically regulate gene expression in a tissue-specific manner(1–3). However, the 3D organization of chromosomes during human brain development and its role in regulating gene networks dysregulated in neurodevelopmental disorders, such as...

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Detaylı Bibliyografya
Yayımlandı:Nature
Asıl Yazarlar: Won, Hyejung, de la Torre-Ubieta, Luis, Stein, Jason L., Parikshak, Neelroop N., Huang, Jerry, Opland, Carli K., Gandal, Michael, Sutton, Gavin J., Hormozdiari, Farhad, Lu, Daning, Lee, Changhoon, Eskin, Eleazar, Voineagu, Irina, Ernst, Jason, Geschwind, Daniel H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358922/
https://ncbi.nlm.nih.gov/pubmed/27760116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature19847
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