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Chromosome conformation elucidates regulatory relationships in developing human brain
Three-dimensional physical interactions within chromosomes dynamically regulate gene expression in a tissue-specific manner(1–3). However, the 3D organization of chromosomes during human brain development and its role in regulating gene networks dysregulated in neurodevelopmental disorders, such as...
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| 發表在: | Nature |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5358922/ https://ncbi.nlm.nih.gov/pubmed/27760116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature19847 |
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