KUS121, a VCP modulator, attenuates ischemic retinal cell death via suppressing endoplasmic reticulum stress

Ischemic neural damages cause several devastating diseases, including brain stroke and ischemic retinopathies, and endoplasmic reticulum (ER) stress has been proposed to be the underlying mechanism of the neuronal cell death of these conditions. We previously synthesized Kyoto University substances...

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Gepubliceerd in:Sci Rep
Hoofdauteurs: Hata, Masayuki, Ikeda, Hanako O., Kikkawa, Chinami, Iwai, Sachiko, Muraoka, Yuki, Hasegawa, Tomoko, Kakizuka, Akira, Yoshimura, Nagahisa
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5357950/
https://ncbi.nlm.nih.gov/pubmed/28317920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44873
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