Priming of transcriptional memory responses via the chromatin accessibility landscape in T cells

Memory T cells exhibit transcriptional memory and “remember” their previous pathogenic encounter to increase transcription on re-infection. However, how this transcriptional priming response is regulated is unknown. Here we performed global FAIRE-seq profiling of chromatin accessibility in a human T...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Tu, Wen Juan, Hardy, Kristine, Sutton, Christopher R., McCuaig, Robert, Li, Jasmine, Dunn, Jenny, Tan, Abel, Brezar, Vedran, Morris, Melanie, Denyer, Gareth, Lee, Sau Kuen, Turner, Stephen J., Seddiki, Nabila, Smith, Corey, Khanna, Rajiv, Rao, Sudha
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5357947/
https://ncbi.nlm.nih.gov/pubmed/28317936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44825
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