Priming of transcriptional memory responses via the chromatin accessibility landscape in T cells

Memory T cells exhibit transcriptional memory and “remember” their previous pathogenic encounter to increase transcription on re-infection. However, how this transcriptional priming response is regulated is unknown. Here we performed global FAIRE-seq profiling of chromatin accessibility in a human T...

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Pubblicato in:Sci Rep
Autori principali: Tu, Wen Juan, Hardy, Kristine, Sutton, Christopher R., McCuaig, Robert, Li, Jasmine, Dunn, Jenny, Tan, Abel, Brezar, Vedran, Morris, Melanie, Denyer, Gareth, Lee, Sau Kuen, Turner, Stephen J., Seddiki, Nabila, Smith, Corey, Khanna, Rajiv, Rao, Sudha
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5357947/
https://ncbi.nlm.nih.gov/pubmed/28317936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44825
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