Priming of transcriptional memory responses via the chromatin accessibility landscape in T cells

Memory T cells exhibit transcriptional memory and “remember” their previous pathogenic encounter to increase transcription on re-infection. However, how this transcriptional priming response is regulated is unknown. Here we performed global FAIRE-seq profiling of chromatin accessibility in a human T...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tu, Wen Juan, Hardy, Kristine, Sutton, Christopher R., McCuaig, Robert, Li, Jasmine, Dunn, Jenny, Tan, Abel, Brezar, Vedran, Morris, Melanie, Denyer, Gareth, Lee, Sau Kuen, Turner, Stephen J., Seddiki, Nabila, Smith, Corey, Khanna, Rajiv, Rao, Sudha
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5357947/
https://ncbi.nlm.nih.gov/pubmed/28317936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44825
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