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Absence of renal enlargement in fructose‐fed proximal‐tubule‐select insulin receptor (IR), insulin‐like‐growth factor receptor (IGF1R) double knockout mice
The major site of fructose metabolism in the kidney is the proximal tubule (PT). To test whether insulin and/or IGF1 signaling in the PT is involved in renal structural/functional responses to dietary fructose, we bred mice with dual knockout (KO) of the insulin receptor (IR) and the IGF1 receptor (...
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| Publicado no: | Physiol Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5357825/ https://ncbi.nlm.nih.gov/pubmed/27923977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13052 |
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