Deletion of the Insulin Receptor in the Proximal Tubule Promotes Hyperglycemia

Nearly all renal tubular epithelial cells express insulin receptor. The insulin receptor in the distal tubule appears to modulate BP, but the role of the insulin receptor in the proximal tubule is unknown. Here, we selectively knocked out the insulin receptor from the proximal tubules of mice. Weste...

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Detalhes bibliográficos
Main Authors: Tiwari, Swasti, Singh, Ravi Shankar, Li, Lijun, Tsukerman, Susanna, Godbole, Madan, Pandey, Gaurav, Ecelbarger, Carolyn M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2013
Assuntos:
Brief Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736710/
https://ncbi.nlm.nih.gov/pubmed/23723425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012060628
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