Chemokine Receptor CXCR3 Deficiency Exacerbates Murine Autoimmune Cholangitis by Promoting Pathogenic CD8+ T Cell Activation

CXC Chemokine Receptor 3 (CXCR3) is functionally pleiotropic and not only plays an important role in chemotaxis, but also participates in T cell differentiation and may play a critical role in inducing and maintaining immune tolerance. These observations are particularly critical for autoimmune chol...

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Detalhes bibliográficos
Publicado no:J Autoimmun
Main Authors: Ma, Hong-Di, Ma, Wen-Tao, Liu, Qing-Zhi, Zhao, Zhi-Bin, Liu, Mu-Zi-Ying, Tsuneyama, Koichi, Gao, Jin-Ming, Ridgway, William M., Ansari, Aftab A., Gershwin, M. Eric, Fei, Yun-Yun, Lian, Zhe-Xiong
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5357510/
https://ncbi.nlm.nih.gov/pubmed/28129932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2016.12.012
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