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Polymorphisms in the multidrug-resistance 1 gene related to glucocorticoid response in rheumatoid arthritis treatment
A substantial proportion of rheumatoid arthritis (RA)-patients experience an insufficient response to glucocorticoids, an important therapeutic agent in RA. The multidrug-resistance 1 (MDR1) gene product P-glycoprotein (P-gp) is an efflux pump that actively transports substrates, such as glucocortic...
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Gepubliceerd in: | Rheumatol Int |
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Hoofdauteurs: | , , , , , , , , |
Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
Springer Berlin Heidelberg
2017
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5357283/ https://ncbi.nlm.nih.gov/pubmed/28132103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00296-017-3653-1 |
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