Exploring the Inflammatory Metabolomic Profile to Predict Response to TNF-α Inhibitors in Rheumatoid Arthritis

In clinical practice, approximately one-third of patients with rheumatoid arthritis (RA) respond insufficiently to TNF-α inhibitors (TNFis). The aim of the study was to explore the use of a metabolomics to identify predictors for the outcome of TNFi therapy, and study the metabolomic fingerprint in...

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Bibliographic Details
Published in:PLoS One
Main Authors: Cuppen, Bart V. J., Fu, Junzeng, van Wietmarschen, Herman A., Harms, Amy C., Koval, Slavik, Marijnissen, Anne C. A., Peeters, Judith J. W., Bijlsma, Johannes W. J., Tekstra, Janneke, van Laar, Jacob M., Hankemeier, Thomas, Lafeber, Floris P. J. G., van der Greef, Jan
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025050/
https://ncbi.nlm.nih.gov/pubmed/27631111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163087
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