Exploring the Inflammatory Metabolomic Profile to Predict Response to TNF-α Inhibitors in Rheumatoid Arthritis

In clinical practice, approximately one-third of patients with rheumatoid arthritis (RA) respond insufficiently to TNF-α inhibitors (TNFis). The aim of the study was to explore the use of a metabolomics to identify predictors for the outcome of TNFi therapy, and study the metabolomic fingerprint in...

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發表在:PLoS One
Main Authors: Cuppen, Bart V. J., Fu, Junzeng, van Wietmarschen, Herman A., Harms, Amy C., Koval, Slavik, Marijnissen, Anne C. A., Peeters, Judith J. W., Bijlsma, Johannes W. J., Tekstra, Janneke, van Laar, Jacob M., Hankemeier, Thomas, Lafeber, Floris P. J. G., van der Greef, Jan
格式: Artigo
語言:Inglês
出版: Public Library of Science 2016
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025050/
https://ncbi.nlm.nih.gov/pubmed/27631111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163087
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