Exploring the Inflammatory Metabolomic Profile to Predict Response to TNF-α Inhibitors in Rheumatoid Arthritis

In clinical practice, approximately one-third of patients with rheumatoid arthritis (RA) respond insufficiently to TNF-α inhibitors (TNFis). The aim of the study was to explore the use of a metabolomics to identify predictors for the outcome of TNFi therapy, and study the metabolomic fingerprint in...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Cuppen, Bart V. J., Fu, Junzeng, van Wietmarschen, Herman A., Harms, Amy C., Koval, Slavik, Marijnissen, Anne C. A., Peeters, Judith J. W., Bijlsma, Johannes W. J., Tekstra, Janneke, van Laar, Jacob M., Hankemeier, Thomas, Lafeber, Floris P. J. G., van der Greef, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025050/
https://ncbi.nlm.nih.gov/pubmed/27631111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163087
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