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Tocilizumab as monotherapy or combination therapy for treating active rheumatoid arthritis: a meta-analysis of efficacy and safety reported in randomized controlled trials

BACKGROUND: Previous studies in patients with rheumatoid arthritis (RA) have shown that switching to tocilizumab (TCZ) monotherapy (TCZ(MONO)) or combination therapy (TCZ(COMBI)) with conventional synthetic disease-modifying anti-rheumatic drugs (csDMARDs) is efficacious in reducing disease activity...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Teitsma, Xavier M., Marijnissen, Anne Karien A., Bijlsma, Johannes W. J., Lafeber, Floris P. J., Jacobs, Johannes W. G.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034420/
https://ncbi.nlm.nih.gov/pubmed/27658491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-016-1108-9
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